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RSK2-inactivating mutations potentiate MAPK signaling and support cholesterol metabolism in hepatocellular carcinoma

Lo‐Kong Chan, Daniel Wai‐Hung Ho, Charles Shing Kam, Elley Yung-Tuen Chiu, Irene Lo, Derek Yau, Elaine Cheung, C N Tang, Victor Wai-Lun Tang, Terence K. Lee, Carmen Chak‐Lui Wong, Ksh Chok, Albert Chan, Tan To Cheung, Chun‐Ming Wong, Irene Oi‐Lin Ng

2020Journal of Hepatology56 citationsDOI

Topics & Concepts

HCCSCancer researchBiologySorafenibMAPK/ERK pathwayKinaseHepatocellular carcinomaMolecular biologyGeneticsMelanoma and MAPK PathwaysHepatocellular Carcinoma Treatment and PrognosisCancer Mechanisms and Therapy
RSK2-inactivating mutations potentiate MAPK signaling and support cholesterol metabolism in hepatocellular carcinoma | Litcius