Lyophilization as an effective tool to develop AAV8 gene therapy products for refrigerated storage
Li Zhi, Yao Chen, Kuan-Yu Lai, Jonathan Wert, Shuai Li, Xiaoyan Wang, Xiaolin Tang, Mohammed Shameem, Dingjiang Liu
Topics & Concepts
CryoprotectantFreeze-dryingMannitolChromatographyChemistryRecombinant DNAExcipientGenetic enhancementBiochemistryBiologyGeneCryopreservationCell biologyEmbryoVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in InsectsCAR-T cell therapy research