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Synthesis, biological evaluation and action mechanism of 7H-[1,2,4] triazolo [3,4-b] [1,3,4] thiadiazine-phenylhydrazone derivatives as α-glucosidase inhibitors

Qianqian Feng, Jinfeng Zhang, Shuang Luo, Yong Huang, Zhiyun Peng, Guangcheng Wang

2023European Journal of Medicinal Chemistry26 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryAcarboseStereochemistryIC50In vivoDocking (animal)CytotoxicityMechanism of actionCircular dichroismPostprandialProton NMRActive siteCarbon-13 NMREnzymePotencyIn vitroBiochemistryMedicineBiologyEndocrinologyNursingInsulinBiotechnologySynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsClick Chemistry and Applications
Synthesis, biological evaluation and action mechanism of 7H-[1,2,4] triazolo [3,4-b] [1,3,4] thiadiazine-phenylhydrazone derivatives as α-glucosidase inhibitors | Litcius