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Synthesis and clinical application of representative small-molecule dipeptidyl Peptidase-4 (DPP-4) inhibitors for the treatment of type 2 diabetes mellitus (T2DM)

Dong-Wei Shao, Li-Jie Zhao, Jinfeng Sun

2024European Journal of Medicinal Chemistry25 citationsDOIOpen Access PDF

Topics & Concepts

Type 2 Diabetes MellitusGlucose homeostasisDipeptidyl peptidase-4Diabetes mellitusPharmacologyChemistryMedicinePharmacodynamicsDrugType 2 diabetesEndocrinologyPharmacokineticsInsulin resistanceDiabetes Treatment and ManagementPeptidase Inhibition and AnalysisNeuropeptides and Animal Physiology
Synthesis and clinical application of representative small-molecule dipeptidyl Peptidase-4 (DPP-4) inhibitors for the treatment of type 2 diabetes mellitus (T2DM) | Litcius