Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight
Song‐Yang Zhang, Kyla Bruce, Zahra Danaei, Rosa J.W. Li, Daniel R. Barros, Rachel Kuah, Yu-Mi Lim, Laura H. Mariani, David Z.I. Cherney, Jennifer F.M. Chiu, Heather N. Reich, Tony K.T. Lam
Topics & Concepts
GDF15MetforminEndocrinologyInternal medicineArea postremaEnergy homeostasisGlial cell line-derived neurotrophic factorGene knockdownKidneyMedicineBiologyDiabetes mellitusReceptorApoptosisNeurotrophic factorsBiochemistryGDF15 and Related BiomarkersNutrition and Health in AgingMacrophage Migration Inhibitory Factor