Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
Kewen Lei, Armand Kurum, Murat Kaynak, Lucia Bonati, Yulong Han, Veronika Cencen, Min Gao, Yuqing Xie, Yugang Guo, Mélanie T. M. Hannebelle, Yangping Wu, Guanyu Zhou, Ming Guo, Georg E. Fantner, Mahmut Selman Sakar, Li Tang
Topics & Concepts
Cancer cellCancer immunotherapyCancer researchAdoptive cell transferT cellCytotoxic T cellCytotoxicityImmunotherapyCellCancerBiologyImmunologyCell biologyChemistryImmune systemBiochemistryGeneticsIn vitroImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy research