Integrated serum pharmacochemistry, network pharmacology and pharmacokinetics to explore bioactive components of Gushudan in the treatment of osteoporosis
Li Ren, Qiuyu Li, Liwei Zhang, Ruoyao Wang, Feng Qin, Longshan Zhao, Xiuyan Wei, Zhili Xiong
Topics & Concepts
PharmacokineticsChemistryBergaptenPharmacologyChromatographyImperatorinCmaxLimoninOrbitrapMass spectrometryHigh-performance liquid chromatographyPsoralenMedicineBiochemistryDNAMedicinal Plant Pharmacodynamics ResearchTraditional Chinese Medicine AnalysisInflammatory mediators and NSAID effects