Unleashing the potential of cell membrane-based nanoparticles for COVID-19 treatment and vaccination
Miguel Pereira‐Silva, Gaurav Chauhan, Matthew D. Shin, Clare Hoskins, Marc Madou, Sergio O. Martínez‐Chapa, Nicole F. Steinmetz, Francisco Veiga, Ana Cláudia Paiva‐Santos
Abstract
: Nano-based approaches have received widespread interest regarding enhanced antigen delivery, prolonged blood circulation half-life and controlled release of drugs. Cell membrane-based nanoparticles comprise interesting antiviral multifunctional nanoplatforms for blocking SARS-CoV-2 binding to host cells, reducing inflammation through cytokine neutralization and improving drug delivery toward COVID-19 treatment.
Topics & Concepts
CoronavirusDrug deliveryImmune systemTargeted drug deliveryCellMedicineCoronavirus disease 2019 (COVID-19)VaccinationMembraneDiseaseNanotechnologyImmunologyChemistryMaterials scienceInfectious disease (medical specialty)PathologyBiochemistrySARS-CoV-2 and COVID-19 ResearchBacterial Infections and VaccinesInhalation and Respiratory Drug Delivery