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Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway

Jingpei Liang, Yuanming He, Yao‐Li Cui, Yuening Sun, Guisong He, Zhi-gang Zhu, Xinliang Mao

2023Acta Pharmacologica Sinica22 citationsDOIOpen Access PDF

Topics & Concepts

PyroptosisProgrammed cell deathApoptosisCell biologyMitochondrionNecroptosisCytochrome cMG132Proteasome inhibitorCytosolChemistryCaspaseBiologyProteasomeBiochemistryEnzymeCell death mechanisms and regulationInflammasome and immune disordersUbiquitin and proteasome pathways
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway | Litcius