ALS2-related disorders in Spanish children
Enrique Nogueira, J. Javier Alarcón, Carmen Garma, Cecilia Paredes
Abstract
ALS2 gene encoding for alsin protein is responsible for neurological disorders due to retrograde degeneration of the upper motor neurons of the pyramidal tracts, inherited in an autosomal recessive manner, and displaying a clinical continuum including the infantile ascending hereditary spastic paraplegiaidentified in three Spanish children presented here.
Topics & Concepts
NeuroradiologyNeurologyNeurosurgerySpasticNeuroscienceMedicineAnatomyPhysical medicine and rehabilitationPediatricsPathologyPsychologyPsychiatryCerebral palsyHereditary Neurological DisordersNeurological diseases and metabolismAmyotrophic Lateral Sclerosis Research