A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands
Kejia Li, Shijie Chen, Keyun Wang, Yan Wang, Xue Li, Yuying Ye, Zheng Fang, Jiawen Lyu, Haiyang Zhu, Yanan Li, Ting Yu, Feng Yang, Xiaolei Zhang, Siqi Guo, Chengfei Ruan, Jiahua Zhou, Qi Wang, Mingming Dong, Cheng Luo, Mingliang Ye
Topics & Concepts
ProteomePeptideTrypsinProteolysisComputational biologyIdentification (biology)BiologyProtein Array AnalysisChemistryBiochemistryEnzymeDNA microarrayGene expressionBotanyGeneAdvanced Proteomics Techniques and ApplicationsClick Chemistry and ApplicationsBiotin and Related Studies