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Recurrence, Reoperation, Pregnancy Rates, and Risk Factors for Recurrence after Ovarian Endometrioma Surgery: Long-Term Follow-Up of 756 Women

Su Hyeon Choi, Sujin Kim, Si Won Lee, Seyeon Won, So Hyun Shim, Nara Lee, Mi Kyoung Kim, Yong Wook Jung, Seok Ju Seong, Mi‐La Kim

2023Yonsei Medical Journal20 citationsDOIOpen Access PDF

Abstract

PURPOSE: The aims of this study were to evaluate the cumulative recurrence, reoperation, and pregnancy rates after ovarian endometrioma surgery at a single institution for more than a 5-year follow-up period. MATERIALS AND METHODS: This study was conducted as a retrospective chart review of patients with ovarian endometrioma who underwent surgery between January 2008 and March 2016. Study subjects included premenopausal women with at least 5 years of follow-up. Exclusion criteria were patients with stage I or II ovarian endometrioma, those who underwent hysterectomy or bilateral oophorectomy, and presence of residual ovarian lesions on the first postoperative ultrasonography at 3-6 months. Recurrence was defined as a cystic mass by ultrasonography. RESULTS: <0.001) were significant risk factors for recurrent endometrioma. Among 315 patients who desired pregnancy, 54.0% were able to have a successful pregnancy and delivery. CONCLUSION: Considering that longer postoperative hormonal treatment is the sole modifiable factor for recurrent endometrioma, we recommend long-term hormonal treatment until subsequent pregnancy, especially in younger women.

Topics & Concepts

MedicineInterquartile rangeHazard ratioPregnancyConfidence intervalRetrospective cohort studyEndometriosisSurgeryOvarian reserveGynecologyObstetricsInfertilityInternal medicineGeneticsBiologyEndometriosis Research and TreatmentUterine Myomas and TreatmentsThyroid and Parathyroid Surgery