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Treatment with the PPARα agonist fenofibrate improves the efficacy of CD8+ T cell therapy for melanoma

Mohadeseh Hasanpourghadi, Arezki Chekaoui, Sophia Kurian, Raj K. Kurupati, Robert Ambrose, Wynetta Giles‐Davis, Amara Saha, Xiaowei Xu, Hildegund C.J. Ertl

2023Molecular Therapy — Oncolytics11 citationsDOIOpen Access PDF

Abstract

expanded TILs.

Topics & Concepts

FenofibrateAgonistMedicineMelanomaCD8Internal medicineOncologyCancer researchReceptorImmunologyImmune systemCAR-T cell therapy researchCancer Immunotherapy and BiomarkersMelanoma and MAPK Pathways
Treatment with the PPARα agonist fenofibrate improves the efficacy of CD8+ T cell therapy for melanoma | Litcius