Glutamine metabolite α-ketoglutarate acts as an epigenetic co-factor to interfere with osteoclast differentiation
Sang-Yong Lee, Hyuk Soon Kim, Myoung Jun Kim, Keun Young Min, Wahn Soo Choi, Jueng Soo You
Topics & Concepts
Downregulation and upregulationChromatin immunoprecipitationRANKLGCLCGlutathioneH3K4me3Transcription factorCell biologyOsteoclastChemistryHistone methylationEpigeneticsMethylationBiologyBiochemistryMolecular biologyActivator (genetics)DNA methylationGene expressionIn vitroPromoterGeneEnzymeBone Metabolism and DiseasesBone health and treatmentsEpigenetics and DNA Methylation