Synthetic lethal combination of CHK1 and WEE1 inhibition for treatment of castration-resistant prostate cancer
Yapeng Chao, Yuzhou Chen, Wenxiao Zheng, Kathryn Demanelis, Yu Liu, Jaclyn Connelly, Hong Wang, Song Li, Qiming J. Wang
Topics & Concepts
Prostate cancerWee1Cancer researchBiologyCancerDNA damageCell cycleCell cycle checkpointCHEK1Cancer cellMitosisPharmacologyCell biologyDNACyclin-dependent kinase 1GeneticsProstate Cancer Treatment and ResearchCancer-related gene regulationRenal and related cancers