Litcius/Paper detail

Artificial Intelligence in Oncology Drug Discovery and Development

John W. Cassidy, Belle Taylor

2020IntechOpen eBooks19 citationsDOIOpen Access PDF

Abstract

There exists a profound conflict at the heart of oncology drug development. The efficiency of the drug development process is falling, leading to higher costs per approved drug, at the same time personalised medicine is limiting the target market of each new medicine. Even as the global economic burden of cancer increases, the current paradigm in drug development is unsustainable. In this book, we discuss the development of techniques in machine learning for improving the efficiency of oncology drug development and delivering cost-effective precision treatment. We consider how to structure data for drug repurposing and target identification, how to improve clinical trials and how patients may view artificial intelligence.

Topics & Concepts

Drug developmentDrug repositioningDrugLimitingDrug discoveryMedicineClinical trialRepurposingIdentification (biology)Intensive care medicineRisk analysis (engineering)OncologyInternal medicinePharmacologyBioinformaticsEngineeringBiologyMechanical engineeringBotanyWaste managementComputational Drug Discovery MethodsGenetics, Bioinformatics, and Biomedical Research