Delivery of gefitinib loaded nanoparticles for effectively inhibiting prostate cancer progression
Zhi Xiong, Tong Tong, Zhaoxiang Xie, Shun-Li Yu, Ruilin Zhuang, Qiang Jia, Shirong Peng, Bingheng Li, Junjia Xie, Kaiwen Li, Jun Wu, Hai Huang
Abstract
, it has been verified that GEF@PLGA NPs exhibit selective accumulation in the tumor and effectively restrain tumor growth. Therefore, the GEF@PLGA NPs hold great promise for the treatment of PCa.
Topics & Concepts
GefitinibProstate cancerIn vivoPLGADrug deliveryCancer researchChemistryPharmacologyEpidermal growth factor receptorDrugBiocompatibilityCancerMedicineIn vitroInternal medicineBiochemistryBiologyOrganic chemistryBiotechnologyPeptidase Inhibition and AnalysisProstate Cancer Treatment and ResearchHepatocellular Carcinoma Treatment and Prognosis