Promoting the adoption of best practices and standards to enhance quality and reproducibility of stem cell research
Lucia Selfa Aspiroz, Milena Mennecozzi, Laura Batlle‐Morera, Barbara Corneo, Lyn Healy, Mark Kotter, Armin Kurtz, Tenneille E. Ludwig, Christine L. Mummery, Martín F. Pera, Glyn Stacey, Carlos A. Tristan, Maurice Whelan
Abstract
Advancing the use of human stem cell-based models on preclinical and regulatory testing fields requires the performance of rigorous and reproducible research. Quality standards and reporting best practices should be promoted to ensure the reliability and translatability of stem cell models and results. Strategies to increase awareness and implementation of best practices and standards will require training initiatives and collaboration across relevant stakeholders. Overall, improving the quality and reproducibility of stem cell-based models and methods through best practices and standards will accelerate their adoption in industrial and regulatory contexts and ultimately drive the development of effective therapies and safer chemicals.