High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development
Jithesh Kottur, Olga Rechkoblit, Richard Quintana‐Feliciano, Daniela Sciaky, Aneel K. Aggarwal
Topics & Concepts
MethyltransferaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CoronavirusCoronavirus disease 2019 (COVID-19)Core (optical fiber)2019-20 coronavirus outbreakO-methyltransferaseBiologyComputational biologyResolution (logic)Severe acute respiratory syndrome coronavirusVirologyGeneticsComputer scienceMethylationMedicineDNAInfectious disease (medical specialty)DiseaseArtificial intelligencePathologyTelecommunicationsOutbreakBacteriophages and microbial interactionsPeptidase Inhibition and AnalysisRNA and protein synthesis mechanisms