De novo case of lichenoid eruption following dupilumab treatment
Tae‐Eun Kim, Min Kyung Shin
Abstract
Lichenoid drug eruption is an uncommon adverse effect of several drugs, including antihypertensives, diuretics, and antimalarials. The pathogenesis has not been completely identified. As in lichen planus, activation of CD8+ autocytotoxic T lymphocytes promoted by helper T (Th) cell type 1 immune response seems to be the crucial pathophysiologic factor.1
Topics & Concepts
MedicineDupilumabDrug eruptionDermatologyAdverse effectImmunologyCD8PathogenesisImmune systemDrugPharmacologyAtopic dermatitisDermatology and Skin DiseasesOral Health Pathology and TreatmentAutoimmune Bullous Skin Diseases