Remimazolam reduces sepsis-associated acute liver injury by activation of peripheral benzodiazepine receptors and p38 inhibition of macrophages
Haihong Fang, Yidong Zhang, Jiancheng Wang, Lulan Li, Sheng An, Qiaobing Huang, Zhongqing Chen, Hong Yang, Jie Wu, Zhenhua Zeng
Topics & Concepts
Proinflammatory cytokineMedicinePharmacologyLiver injuryChemokineInflammationLipopolysaccharideBenzodiazepineSepsisp38 mitogen-activated protein kinasesCytokineReceptorImmunologyInternal medicineBiologySignal transductionMAPK/ERK pathwayBiochemistryIntensive Care Unit Cognitive DisordersDrug-Induced Hepatotoxicity and ProtectionPain Mechanisms and Treatments