The immunologic changes during different phases of intestinal anastomotic healing
Feng Zhang, Song Qiao, Chunqiao Li, Bo Wu, Stefan Reischl, Philipp‐Alexander Neumann
Abstract
Intestinal anatomosis is a complex and multicellular process that involving three overlapped phases: exudative phase, proliferative phase, and reparative phase. Undisturbed anastomotic healings are crucial for the recovery of patients after operations but unsuccessful healings are linked with a considerable mortality. This time, we concentrate on the immunologic changes during different phases of intestinal anastomotic healing and select several major immune cells and cytokines of each phase to get a better understanding of these immunologic changes in different phases, which will be significant for more precise therapy strategies in anastomoses.
Topics & Concepts
AnastomosisImmune systemPhase (matter)ImmunologyMedicineSurgeryChemistryOrganic chemistryColorectal Cancer Surgical TreatmentsCancer Cells and MetastasisWound Healing and Treatments