Invasive Cervical Cancer Risk Among HIV-Infected Women: A North American Multicohort Collaboration Prospective Study
Gypsyamber DʼSouza, Eric A. Engels, Michael J. Silverberg, Sonia Napravnik, Alison G. Abraham, Anita Rachlis, Sean B. Rourke, Robert Dubrow, Yuezhou Jing, Ronald J. Bosch, Gregory D. Kirk, Richard D. Moore, M. John Gill, Nancy A. Hessol, Robert S. Hogg, John T. Brooks, Joseph J. Eron, Timothy R. Sterling, Howard D. Strickler, James J. Goedert, Kelly A. Gebo, Stephen J. Gange, Mari M. Kitahata, Michael S. Saag, Heidi M. Crane, Marina B. Klein
Abstract
HIV infection and low CD4+ T-cell count are associated with an increased risk of persistent oncogenic HPV infection – the major risk factor for cervical cancer. Few reported prospective cohort studies have characterized the incidence of invasive cervical cancer (ICC) in HIV-infected women.
Topics & Concepts
Human immunodeficiency virus (HIV)Cervical cancerMedicineProspective cohort studyOncologyInternal medicineHuman papillomavirusEnvironmental healthCancerDemographyGynecologyFamily medicineSociologyCervical Cancer and HPV Research