MiR-15b and miR-16 suppress TGF-β1-induced proliferation and fibrogenesis by regulating LOXL1 in hepatic stellate cells
Li Ma, Junping Liu, Erhui Xiao, Huibin Ning, Kuan Li, Jia Shang, Yi Kang
Topics & Concepts
Hepatic stellate cellDownregulation and upregulationGene knockdownCell growthCell biologyCancer researchHepatic fibrosismicroRNATransforming growth factorChemistryFibrosisBiologyMolecular biologyCell cultureMedicineInternal medicineEndocrinologyGeneBiochemistryGeneticsLiver physiology and pathologyMacrophage Migration Inhibitory FactorOrgan Transplantation Techniques and Outcomes