A Bidentate Ru(II)-NC Complex as a Catalyst for Semihydrogenation of Alkynes to (<i>E</i>)-Alkenes with Ethanol
Dawei Gong, Bowen Hu, Weiwei Yang, Degong Kong, Haiping Xia, Dafa Chen
Abstract
Four Ru(II)-NC complexes were tested as catalysts for semihydrogenation of internal alkynes to (E)-alkenes with ethanol, and the complex {(C5H4N)(C6H4)}RuCl(CO)(PPh3)2 (1a) showed the highest activity. The reactions proceeded well with 1 mol % catalyst loading and 0.1 equiv of t-BuONa at 110 °C for 1 h, and 32 alkenes were synthesized with excellent E:Z selectivity. This is the first ruthenium-catalyzed semihydrogenation of internal alkynes to (E)-alkenes using ethanol as the hydrogen donor.
Topics & Concepts
ChemistryCatalysisRutheniumEthanolDenticitySelectivityMedicinal chemistryHydrogenOrganic chemistryMetalAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisMetal-Organic Frameworks: Synthesis and Applications