Genome editing in human hematopoietic stem and progenitor cells via CRISPR-Cas9-mediated homology-independent targeted integration
Hanan Bloomer, Richard H. Smith, Waleed Hakami, André Larochelle
Topics & Concepts
CRISPRGenome editingBiologyHaematopoiesisProgenitor cellStem cellCas9GenomeComputational biologyHomology (biology)GeneticsGeneCRISPR and Genetic EngineeringCAR-T cell therapy researchVirus-based gene therapy research