Rational design of molecular rotor-based fluorescent probes with bi-aromatic rings for efficient in vivo detection of amyloid-β plaques in Alzheimer's disease
Nan Yue, Hualong Fu, Yimin Chen, Xi Gao, Jiapei Dai, Mengchao Cui
Topics & Concepts
ChemistryFluorescenceIn vivoBiophysicsGenetically modified mouseTransgeneFluorescence-lifetime imaging microscopyMolecular imagingAmyloid βPyridineEx vivoAmyloid (mycology)In vitroPhotochemistryBiochemistryPathologyGeneDiseaseOrganic chemistryInorganic chemistryPhysicsMedicineQuantum mechanicsBiotechnologyBiologyMolecular Sensors and Ion DetectionAlzheimer's disease research and treatmentsSupramolecular Self-Assembly in Materials