Quantification of tissue sodium concentration in the ischemic stroke: A comparison between external and internal references for 23Na MRI
Anne Adlung, Christian Licht, Simon Reichert, Safa Özdemir, Sherif A. Mohamed, Melina Samartzi, Marc Fatar, Achim Gass, Eva Neumaier Prost, Lothar R. Schad
Abstract
• 23 Na MRI enables the quantification of tissue sodium concentration (TSC). • TSC quantification is primarily performed based on external reference phantoms. • Internal references have the potential to simplify 23Na MR imaging. • CSF and the vitreous humor as internal references on 50 stroke patients. • Quantification based on the vitreous humor provided most robust results.
Topics & Concepts
Brain tissueStroke (engine)Ischemic strokeSodiumMagnetic resonance imagingBiomedical engineeringMedicineNuclear medicineMaterials scienceRadiologyPhysicsIschemiaInternal medicineThermodynamicsMetallurgyAdvanced MRI Techniques and ApplicationsMRI in cancer diagnosisAdvanced Neuroimaging Techniques and Applications