Outbreak of CTX-M-15 Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae ST394 in a French Intensive Care Unit Dedicated to COVID-19
Cécile Emeraud, Samy Figueiredo, Rémy A. Bonnin, Mouna Khecharem, Souad Ouzani, Pierre-Étienne Leblanc, Agnès B. Jousset, Nicolas Fortineau, Jacques Duranteau, Laurent Dortet
Abstract
Infections caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae (ESBL-KP) are constantly rising worldwide and are often reported as causative agent of outbreaks in intensive care units (ICUs). During the first wave of the COVID-19 pandemic, bacterial cross-transmission was thought unlikely to occur due to the reinforcement of hygiene measures and prevention control. However, we report here an ESBL-producing K. pneumoniae (ST394) isolate responsible for a nosocomial outbreak in an ICU dedicated to COVID-19 patients.
Topics & Concepts
Klebsiella pneumoniaeOutbreakIntensive care unitPandemicTransmission (telecommunications)Infection controlHygieneCoronavirus disease 2019 (COVID-19)MedicineIntensive careMicrobiologyVirologyIntensive care medicineBiologyInternal medicineDiseaseInfectious disease (medical specialty)Escherichia coliComputer sciencePathologyTelecommunicationsGeneBiochemistryAntibiotic Resistance in BacteriaAntibiotic Use and ResistanceBacterial biofilms and quorum sensing