Quadruple therapy for asymptomatic COVID-19 infection patients
Ling Wang, Xiaopeng Xu, Junshan Ruan, Saijin Lin, Jinhua Jiang, Hong Ye
Abstract
INTRODUCTION: The novel coronavirus (COVID-19) is currently in epidemic stage. After large-scale interpersonal infection, asymptomatic patients appear. Whether asymptomatic patients are contagious or not and whether they need medication are the arguments among clinical experts. AREAS COVERED: This paper reports a special asymptomatic couple with COVID-19, of which the male patient is an intercity bus driver but has not induced confirmed infection of his 188 passengers. The patients were treated with four combinations of lopinavir/ritonavir tablets, arbidol tablets, Lianhuaqingwen granules, and recombinant human interferon-α2b (IFN-α2b) injection via aerosol. Their clinical characteristics and medication were summarized and analyzed. EXPERT OPINION: . The evidence-based medicine of Lianhuaqingwen granules for treating various viral infections is just based on Chinese patients.