Litcius/Paper detail

4-methylpyrazole protects against acetaminophen-induced acute kidney injury

Jephte Y. Akakpo, Anup Ramachandran, Hi̇lmi̇ Orhan, Steven C. Curry, Barry H. Rumack, Hartmut Jaeschke

2020Toxicology and Applied Pharmacology69 citationsDOIOpen Access PDF

Topics & Concepts

AcetaminophenNephrotoxicityCYP2E1Liver injuryKidneyAcute kidney injuryPharmacologyMetaboliteChemistryGlutathioneToxicityMedicineInternal medicineBiochemistryMetabolismEnzymeCytochrome P450Drug-Induced Hepatotoxicity and ProtectionLiver Disease and TransplantationDrug Transport and Resistance Mechanisms