Litcius/Paper detail

USP8 promotes cancer progression and extracellular vesicle‐mediated CD8+ T cell exhaustion by deubiquitinating the TGF‐β receptor TβRII

Feng Xie, Xiaoxue Zhou, Heyu Li, Peng Su, Sijia Liu, Ran Li, Jing Zou, Wei Xiang, Chen Pan, Zhengkui Zhang, Min Zheng, Zhuang Liu, Xuli Meng, Huib Ovaa, Peter ten Dijke, Fangfang Zhou, Long Zhang

2022The EMBO Journal89 citationsDOIOpen Access PDF

Topics & Concepts

BiologySMADCancer researchTumor microenvironmentCancer immunotherapyMicrovesicleCell biologySignal transductionImmunotherapyImmunologyImmune systemMicrovesiclesBiochemistrymicroRNAGeneTumor cellsUbiquitin and proteasome pathwaysExtracellular vesicles in diseaseImmune cells in cancer
USP8 promotes cancer progression and extracellular vesicle‐mediated CD8+ T cell exhaustion by deubiquitinating the TGF‐β receptor TβRII | Litcius