USP8 promotes cancer progression and extracellular vesicle‐mediated CD8+ T cell exhaustion by deubiquitinating the TGF‐β receptor TβRII
Feng Xie, Xiaoxue Zhou, Heyu Li, Peng Su, Sijia Liu, Ran Li, Jing Zou, Wei Xiang, Chen Pan, Zhengkui Zhang, Min Zheng, Zhuang Liu, Xuli Meng, Huib Ovaa, Peter ten Dijke, Fangfang Zhou, Long Zhang
Topics & Concepts
BiologySMADCancer researchTumor microenvironmentCancer immunotherapyMicrovesicleCell biologySignal transductionImmunotherapyImmunologyImmune systemMicrovesiclesBiochemistrymicroRNAGeneTumor cellsUbiquitin and proteasome pathwaysExtracellular vesicles in diseaseImmune cells in cancer