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Higenamine mitigates interleukin-1β-induced human nucleus pulposus cell apoptosis by ROS-mediated PI3K/Akt signaling

Xiaojuan Zhu, Shichao Liu, Zhijiao Cao, Lei Yang, Fang Lü, Yulan Li, Lili Hu, Xiaoliang Bai

2021Molecular and Cellular Biochemistry27 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayProtein kinase BApoptosisTUNEL assayCell biologyChemistrySignal transductionReactive oxygen speciesLY294002PhosphatidylinositolBiologyBiochemistryBioactive Natural Diterpenoids ResearchDrug-Induced Hepatotoxicity and ProtectionPlant-based Medicinal Research
Higenamine mitigates interleukin-1β-induced human nucleus pulposus cell apoptosis by ROS-mediated PI3K/Akt signaling | Litcius