Jervine inhibits non-small cell lung cancer (NSCLC) progression by suppressing Hedgehog and AKT signaling via triggering autophagy-regulated apoptosis
Wei Lei, Zhenyun Huo
Topics & Concepts
SmoothenedAutophagyGLI1PI3K/AKT/mTOR pathwayCancer researchApoptosisProtein kinase BHedgehog signaling pathwayBiologyPatchedHedgehogSignal transductionLung cancerOncogeneChemistryCell biologyCell cycleMedicineInternal medicineBiochemistryHedgehog Signaling Pathway StudiesEpigenetics and DNA MethylationCancer-related Molecular Pathways