Modular Peptide Probe for Pre/Intra/Postoperative Therapeutic to Reduce Recurrence in Ovarian Cancer
Jun Dai, Yong Cheng, Jun Wu, Quan Wang, Wenwen Wang, Juliang Yang, Zujin Zhao, Xiaoding Lou, Fan Xia, Shixuan Wang, Ben Zhong Tang
Abstract
TMP/VEGF-siRNA) therapeutic system and abbreviated as the PIP therapeutic system, which reduced the recurrence of ovarian cancer in subcutaneous tumor models, intraperitoneal metastasis models, and patient-derived tumor xenograft models. Our findings provide a therapeutic system based on modular peptide probes to reduce the recurrence of ovarian cancer after surgery, which provides a perspective for the surgical management of ovarian cancer.
Topics & Concepts
Ovarian cancerMedicineMetastasisAdjuvantCancerIn vivoPhotodynamic therapyCancer researchOncologyInternal medicineBiologyChemistryBiotechnologyOrganic chemistryNanoplatforms for cancer theranosticsRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques