Spiroindole-containing compounds bearing phosphonate group of potential Mpro-SARS-CoV-2 inhibitory properties
Mohamed S. Bekheit, Siva S. Panda, Benson M. Kariuki, Sara H. Mahmoud, Ahmed Mostafa, Adel S. Girgis
Topics & Concepts
ChemistryPhosphonateSarcosinePyrrolidineStereochemistrySelectivityVero cellDocking (animal)IndolineInhibitory postsynaptic potentialCombinatorial chemistryAmino acidOrganic chemistryIn vitroBiochemistryGlycineBiologyNursingCatalysisMedicineNeuroscienceSynthesis and biological activityQuinazolinone synthesis and applicationsSynthesis and Characterization of Heterocyclic Compounds