Litcius/Paper detail

Bioisosteric investigation of ebselen: Synthesis and in vitro characterization of 1,2-benzisothiazol-3(2H)-one derivatives as potent New Delhi metallo-β-lactamase inhibitors

Wenbin Jin, Chen Xu, Qipeng Cheung, Wei Gao, Ping Zeng, Jun Liu, Edward Wai‐Chi Chan, Yun‐Chung Leung, Tak Hang Chan, Kwok‐Yin Wong, Sheng Chen, Kin‐Fai Chan

2020Bioorganic Chemistry30 citationsDOI

Topics & Concepts

MeropenemChemistryEbselenCytotoxicityBioisostereMoietyIC50In vitroPharmacologyEffluxStereochemistryCombinatorial chemistryBiochemistryEnzymeAntibioticsChemical synthesisAntibiotic resistanceBiologyGlutathione peroxidaseGlutathioneAntibiotic Resistance in BacteriaPhenothiazines and Benzothiazines Synthesis and ActivitiesCancer therapeutics and mechanisms