Highland barley β-glucan supplementation attenuated hepatic lipid accumulation in Western diet-induced non-alcoholic fatty liver disease mice by modulating gut microbiota
Huicui Liu, Chenxi Nie, Xinzhong Hu, Juxiu Li
Abstract
) as well as SCFA contents. The increase in SCFA contents might activate the adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) signaling pathway, thereby improving the liver lipid metabolism disorder and reducing liver lipid deposition.
Topics & Concepts
Fatty liverGlucanGut floraAlcoholic liver diseaseLipid metabolismWestern dietLipid accumulationBiologyBiochemistryBeta-glucanChemistryDiseaseMicrobiologyMedicineInternal medicineEndocrinologyCirrhosisObesityLiver Disease Diagnosis and TreatmentGut microbiota and healthDiet, Metabolism, and Disease