Litcius/Paper detail

Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis

Leigh A. Kotzé, Caroline Beltran, Dirk Lang, André G. Loxton, Susan Cooper, Maynard Meiring, Coenraad F.N. Koegelenberg, Brian W. Allwood, Stephanus T. Malherbe, Andriëtte Hiemstra, Brigitte Glanzmann, Craig Kinnear, Gerhard Walzl, Nelita du Plessis

2021mSphere24 citationsDOIOpen Access PDF

Abstract

TB is a highly infectious disease, with granulomas as its hallmark. Granulomas play an important role in the control of M. tuberculosis infection and as such are crucial indicators for our understanding of host resistance to TB.

Topics & Concepts

TuberculosisGranulomaImmune systemMycobacterium tuberculosisImmunologyBiologyDiseasePathologyMedicineTuberculosis Research and EpidemiologyMycobacterium research and diagnosisCytokine Signaling Pathways and Interactions
Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis | Litcius