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MiR-27a-3p overexpression mitigates inflammation and apoptosis of lipopolysaccharides-induced alveolar epithelial cells by targeting FOXO3 and suppressing the activation of NAPDH/ROS

Jian Shang, Lei Wang, Lili Tan, Pan Ren, Dan Wu, Yanfei Xia, Peng Xu

2020Biochemical and Biophysical Research Communications22 citationsDOI

Topics & Concepts

ApoptosisInflammationARDSViability assayFOXO3TransfectionCancer researchA549 cellCell biologyChemistryMolecular biologyBiologyCell cultureLungImmunologyMedicineBiochemistryInternal medicineProtein kinase BGeneticsMicroRNA in disease regulationFOXO transcription factor regulationInflammasome and immune disorders
MiR-27a-3p overexpression mitigates inflammation and apoptosis of lipopolysaccharides-induced alveolar epithelial cells by targeting FOXO3 and suppressing the activation of NAPDH/ROS | Litcius