Optimizations of a novel fluorescence polarization-based high-throughput screening assay for β-catenin/LEF1 interaction inhibitors
Yunyu Chen, Zhenghao Fu, Dongsheng Li, Yuhuan Yue, Xiaoping Liu
Topics & Concepts
High-throughput screeningFluorescenceThroughputFluorescence anisotropyChemistryCateninComputational biologyComputer scienceBiochemistryBiologyPhysicsTelecommunicationsOpticsWirelessWnt signaling pathwayGeneHER2/EGFR in Cancer ResearchWnt/β-catenin signaling in development and cancerAngiogenesis and VEGF in Cancer