Pre-differentiation exposure of PFOA induced persistent changes in DNA methylation and mitochondrial morphology in human dopaminergic-like neurons
Han Zhao, Junkai Xie, Shichen Wu, Oscar F. Sánchez, Xinle Zhang, Jennifer L. Freeman, Chris Yuan
Topics & Concepts
EpigeneticsEpigenomeDNA methylationDopaminergicBiologyChromatinH3K4me3Mitochondrial DNAMitochondrionNeurodegenerationDNA damageCell biologyEndocrinologyInternal medicineDopamineGeneticsDiseaseDNAGene expressionGeneMedicinePromoterPer- and polyfluoroalkyl substances researchBirth, Development, and HealthEffects and risks of endocrine disrupting chemicals