Single-step discovery of high-affinity RNA ligands by UltraSelex
Yaqing Zhang, Yuan Jiang, David Kuster, Qiwei Ye, Wenhao Huang, Simon Fürbacher, Jing‐ye Zhang, Pia Doll, Wenjun Lin, Siwei Dong, Hui Wang, Zhipeng Tang, David Ibberson, Klemens Wild, Irmgard Sinning, Anthony A. Hyman, Andres Jäschke
Topics & Concepts
AptamerComputational biologyRNADrug discoveryNucleic acidSystematic evolution of ligands by exponential enrichmentPolymeraseBiologyChemistryCombinatorial chemistryDNAMolecular biologyBiochemistryGeneAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanismsBacteriophages and microbial interactions