Conflict of interest: the authors declare no conflict of interest.
Samat S. Baygildin, Л. А. Мусина, З. Р. Хисматуллина
Abstract
Retinal degenerations comprise a large heterogeneous class of diseases (dystrophies) of retina leading to a progressive vision loss. The emergence of new experimental therapies (gene and cell therapy, regenerative ophthalmic surgery) generates a demand for new experimental models. The review tackles various animal models of human retinal degenerative diseases. Pros and contras of induced and genetic experimental models are highlighted. An adequate experimental model choice may condition a pathogenetic approach to retinal disease therapy.
Topics & Concepts
RetinalNeuroscienceDiseaseRetinal degenerationConflict of interestMedicineBiologyOphthalmologyPathologyPolitical scienceLawRetinal Development and DisordersOlfactory and Sensory Function StudiesRetinal Diseases and Treatments