Tuning the porosity of biofabricated chitosan membranes in microfluidics with co-assembled nanoparticles as templates
Khanh L. Ly, Christopher B. Raub, Xiaolong Luo
Abstract
synthesized porous CM (pCM) were characterized with scanning electron microscopy and polarized light microscopy. Permeability tests confirmed the increased pore sizes of the pCM and enhanced permeability to macromolecules. Sharper static gradients in three-channel microfluidic devices were demonstrated with the pCM as compared to those with the original CM. The capability to customize the porosity of flow-assembled, freestanding and robust biopolymer membranes inside a microfluidic network is attractive and broadens the applications of these membranes in biomolecular and cellular studies.
Topics & Concepts
MembraneBiopolymerMicrofluidicsGlutaraldehydeMaterials scienceNanoparticlePorosityChitosanChemical engineeringNanotechnologyPolystyrenePermeability (electromagnetism)ChemistryPolymerChromatographyComposite materialBiochemistryEngineeringMicrofluidic and Capillary Electrophoresis ApplicationsMicrofluidic and Bio-sensing TechnologiesInnovative Microfluidic and Catalytic Techniques Innovation