Litcius/Paper detail

Temperature-boosted PAM-less activation of CRISPR-Cas12a combined with selective inhibitors enhances detection of SNVs with VAFs below 0.01%

Kena Chen, Ling Dai, Jie Zhao, Mengjun Deng, Lin Song, Dan Bai, You Wu, Xi Zhou, Yujun Yang, Shuangshuang Yang, Lin Zhao, Xueping Chen, Guoming Xie, Junjie Li, Junjie Li

2023Talanta16 citationsDOI

Topics & Concepts

CRISPRChemistryMutantComputational biologyPoint mutationDNAWild typeMolecular biologyGeneBiologyBiochemistryCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesGenomics and Phylogenetic Studies
Temperature-boosted PAM-less activation of CRISPR-Cas12a combined with selective inhibitors enhances detection of SNVs with VAFs below 0.01% | Litcius