A mitochondrial-targetable dual functional near-infrared fluorescent probe to monitor pH and H<sub>2</sub>O<sub>2</sub> in living cells and mice
Xueyuan Bi, Yingying Wang, Dandan Wang, Li Liu, Wen Zhu, Junjie Zhang, Xiaoming Zha
Abstract
A lower pH level and high hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) concentration in mitochondria is closely associated with a variety of diseases including cancer and inflammation.
Topics & Concepts
FluorescenceChemistryDual (grammatical number)InfraredBiophysicsBiologyPhysicsOpticsLiteratureArtSulfur Compounds in BiologyMolecular Sensors and Ion DetectionNitric Oxide and Endothelin Effects