An Overview of the Pathophysiological Mechanisms of 3-Nitropropionic Acid (3-NPA) as a Neurotoxin in a Huntington's Disease Model and Its Relevance to Drug Discovery and Development
Shubham Upadhayay, Narhari Gangaram Yedke, Vikrant Rahi, Surbhi Singh, Sachin Kumar, Anchal Arora, Priyanka Chandolia, Prabhsharan Kaur, Mandeep Kumar, Prashant Koshal, Sumit Jamwal, Puneet Kumar
Topics & Concepts
NeurotoxinDrug discoveryNeuroscienceBiologyNeuroinflammationGABAergicMitochondrionOxidative stressPharmacologyNeurodegenerationDrug developmentHuntington's diseaseDiseaseDrugBioinformaticsCell biologyMedicineBiochemistryImmunologyPathologyInhibitory postsynaptic potentialInflammationGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyParkinson's Disease Mechanisms and Treatments