An Acridine-Based Fluorescent Sensor for Monitoring ClO− in Water Samples and Zebrafish
Su Chan Lee, Soyoung Park, Haeri So, Gyudong Lee, Ki‐Tae Kim, Cheal Kim
Abstract
A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO− and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, BK was satisfactorily applied for sensing ClO− in water samples and zebrafish.
Topics & Concepts
AcridineFluorescenceChemistryDetection limitAnalyteFormic acidHydrazideAldehydeSelectivityQuenching (fluorescence)ChromatographyOrganic chemistryPhysicsCatalysisQuantum mechanicsMolecular Sensors and Ion DetectionAnalytical Chemistry and SensorsLuminescence and Fluorescent Materials