N-acetylcysteine amide ameliorates mitochondrial dysfunction and reduces oxidative stress in hiPSC-derived dopaminergic neurons with POLG mutation
Kristina Xiao Liang, Guro Helén Vatne, Cecilie Katrin Kristiansen, Oleksandr Ievglevskyi, Elena Kondratskaya, Joel C. Glover, Anbin Chen, Gareth J. Sullivan, Laurence A. Bindoff
Topics & Concepts
BiologyMitochondrial DNAMitochondrionDopaminergicTFAMOxidative stressMitochondrial diseaseCell biologyNeuroscienceGeneticsDopamineEndocrinologyMitochondrial biogenesisGeneMitochondrial Function and PathologyGenetic Neurodegenerative DiseasesPluripotent Stem Cells Research